In our new study, we characterized the topography of age-related evolution of diffusion metrics in neonatal brains. Our results show a rapid decrease in diffusivity metrics of cerebral/cerebellar white matter and vermis in the first few weeks of neonatal age, likely attributable to myelination. In addition, prematurity and low gestational age at birth may result in lasting delay in corpus callosum myelination and cerebral cortex cellularity.
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Bobba, P. S., Weber, C. F., Mak, A., Mozayan, A., Malhotra, A., Sheth, K. N., Taylor, S. N., Vossough, A., Grant, P. E., Scheinost, D., Constable, R. T., Ment, L. R., & Payabvash, S. (2022). Age-related topographic map of magnetic resonance diffusion metrics in neonatal brains. Human brain mapping, 10.1002/hbm.25956. Advance online publication. https://doi.org/10.1002/hbm.25956