Yaryna Bitkovska

Identification of texture MRI brain abnormalities on first-episode psychosis and clinical high-risk subjects using explainable artificial intelligence

Abstract Structural MRI studies in first-episode psychosis and the clinical high-risk state have consistently shown volumetric abnormalities. Aim of the present study was to introduce radiomics texture features in identification of psychosis. Radiomics texture features describe the interrelationship between voxel intensities across multiple spatial scales capturing the hidden information of underlying disease dynamics in addition …

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Talk beim Science Lunch von Frau Wien

Am Mittwoch, den 16.11.2022, findet von 12 – 13 Uhr der Science Lunch statt. Unser Gast ist Frau Wien von dem Dezernat Apotheke, UKSH Lübeck. Sie spricht über das Thema: „Evaluation der Implementierung der Medikationssoftware Meona in der ZIP Lübeck – aktueller Stand“.

Studie zur Alkohol-Abstinenzförderung mit der Firma Dräger

Studie zur Alkohol-Abstinenzförderung mit der Firma Dräger Im Track Sucht läuft zur Zeit eine Studie mit der Firma Dräger, in der untersucht wird, ob mit Hilfe einer neuen App die Abstinenzchancen von frisch entgifteten Alkoholabhängigen verbessert werden können. Binnen der ersten sechs Wochen nach Entgiftung erhalten die Teilnehmer eine ausführliche Diagnostik und im Anschluss daran …

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Association between Alcohol Consumption and Health-Related Quality of Life among Hospital and Ambulatory Care Patients with Past Year Depressive Symptoms

Abstract Background: Little is known about how substance use affects health-related quality of life (HRQOL) in depressed individuals. Here, associations between alcohol consumption and HRQOL in hospital and ambulatory care patients with past-year depressive symptoms are analyzed. Method: The sample consisted of 590 participants (26.8% non-drinkers) recruited via consecutive screenings. Individuals with alcohol use disorders were excluded. …

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[The Well-informed Patient: a Survey on Patients’ Initiative in Seeking Disease-related Information]

Abstract Internet and print media are frequently used by laypersons to learn about health issues. The objective of this study was to find out whether people with mental disorders showed a special pattern of usage. Where and why do they seek for information about their disorder? How do they experience their search? In semi-standardized interviews, …

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Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula

Abstract Based on neuroimaging data, the insula is considered important for people to empathize with the pain of others. Here, we present intracranial electroencephalographic (iEEG) recordings and single-cell recordings from the human insula while seven epilepsy patients rated the intensity of a woman’s painful experiences seen in short movie clips. Pain had to be deduced …

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Study protocol for a randomised controlled trial of an e-health stepped care approach for the treatment of internet use disorders versus a placebo condition: the SCAPIT study

Abstract Introduction: Excessive internet use can lead to problems for some individuals. The WHO has introduced Gaming Disorder in the International Classification of Diseases-11 (ICD-11). Previous research has shown that other internet applications can cause serious mental health problems as well. It is important to provide measures of prevention, early intervention and therapy for internet use …

Study protocol for a randomised controlled trial of an e-health stepped care approach for the treatment of internet use disorders versus a placebo condition: the SCAPIT study Read More »

The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis

Abstract Subtle subjective visual dysfunctions (VisDys) are reported by about 50% of patients with schizophrenia and are suggested to predict psychosis states. Deeper insight into VisDys, particularly in early psychosis states, could foster the understanding of basic disease mechanisms mediating susceptibility to psychosis, and thereby inform preventive interventions. We systematically investigated the relationship between VisDys …

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Striatal resting-state connectivity after long-term diacetylmorphine treatment in opioid-dependent patients

Abstract New treatment approaches for opioid-dependent patients include injectable opioid agonist treatment with diacetylmorphine. While evidence has shown beneficial clinical effects of diacetylmorphine, it is still not clear how long-term diacetylmorphine treatment affects the brain and whether functional brain changes are accompanied by clinical improvements. Therefore, this prospective case-control study focuses on long-term effects of …

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Assessment of Reward-Related Brain Function After a Single Dose of Oxytocin in Autism: A Randomized Controlled Trial

Abstract Background: Autism spectrum disorder (ASD) is characterized by difficulties in social communication and interaction, which have been related to atypical neural processing of rewards, especially in the social domain. As intranasal oxytocin has been shown to modulate activation of the brain’s reward circuit, oxytocin might ameliorate the processing of social rewards in ASD and thus …

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