Yaryna Bitkovska

Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited

The behavioral and cognitive symptoms of severe psychotic disorders overlap with those seen in dementia. However, shared brain alterations remain disputed, and their relevance for patients in at-risk disease stages has not been explored so far. Click here for more information: Koutsouleris, N., …., Lencer, R., Borgwardt, S., … (2022). Exploring Links Between Psychosis and

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How childhood maltreatment alters perception and cognition – the predictive processing account of borderline personality disorder

Borderline personality disorder (BPD) is a severe mental disorder, comprised of heterogeneous psychological and neurobiological pathologies. Here, we propose a predictive processing (PP) account of BPD to integrate these seemingly unrelated pathologies. Reference: Herzog, P., Kube, T., & Fassbinder, E. (2022). How childhood maltreatment alters perception and cognition – the predictive processing account of borderline

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The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis

Subtle subjective visual dysfunctions (VisDys) are reported by about 50% of patients with schizophrenia and are suggested to predict psychosis states. Deeper insight into VisDys, particularly in early psychosis states, could foster the understanding of basic disease mechanisms mediating susceptibility to psychosis, and thereby inform preventive interventions. In this study, we systematically investigated the relationship

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Get to know Prof Dr Rebekka Lencer from “Track Psychosis” better

Today, we would like to introduce the medical head of the “Track Psychosis” – Prof Dr Rebekka Lencer – from the Department of Psychiatry and Psychotherapy. We interviewed Prof Dr Rebekka Lencer and asked her about her impressions of the work in psychiatry: What made you decide to work at the Department of Psychiatry and

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Get to know Prof Dr Jan Philipp Klein from the Track Psychosomatics better

Today we would like to introduce you to the medical head of the “Track Psychosomatics” – Prof Dr Jan Philipp Klein – from the Department of Psychiatry, Psychosomatics and Psychotherapy. To do this in a more exciting way, we interviewed Jan Philipp Klein and asked him some questions about working in Psychiatry that might interest

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Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia

25 patients with schizophrenia with pronounced negative symptoms during psychotic remission and 24 healthy controls were included in this study. Results provide evidence for impaired model-free reward prediction influence as a mechanism for negative symptoms in schizophrenia as well as for reduced associative striatum dopamine and executive dysfunction as relevant factors. Data suggest potential treatment

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