Publications

Special Collection “Hallucinations and Delusions” – call for submissions

Special Collection “Hallucinations and Delusions” – call for submissions Hallucination is understood as the perception of something that is not there and delusion as the belief of something despite contrary evidence. Both are commonly associated with psychiatric conditions such as schizophrenia, Alzheimer’s disease, or bipolar disorder. However, they sometimes also manifest in neurotypicals, for example, …

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Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia

25 patients with schizophrenia with pronounced negative symptoms during psychotic remission and 24 healthy controls were included in this study. Results provide evidence for impaired model-free reward prediction influence as a mechanism for negative symptoms in schizophrenia as well as for reduced associative striatum dopamine and executive dysfunction as relevant factors. Data suggest potential treatment …

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Association of stress-related neural activity and baseline interleukin-6 plasma levels in healthy adults

Phantastic news! The first paper as part of the PhD by Johanna Voges is finally published! In this paper we assessed the link between baseline plasma levels of the cytokine interleukin (IL)-6 and neural markers of psychosocial stress. Using the Montreal Imaging Stress Task (MIST) we scanned 65 healthy individuals and found a negative association between …

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Special Issue “Psychosis: Clinical Management and Challenges” – call for submissions

Special Issue “Psychosis: Clinical Management and Challenges” – call for submissions We are pleased to invite submissions for special issue with the title “Psychosis: Clinical Management and Challenges” in the Journal of Clinical Medicine, an open access journal by MDPI (IF 4.242), edited by Prof. Christina Andreou in collaboration with Prof. Marco Armando and Dr. Luis Alameda …

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Where to put Compulsive Sexual Behavior Disorder (CSBD)? Phenomenology matters •

In this commentary paper, it is discussed if Compulsive Sexual Behavior Disorder (CSBD) is best categorized as an Impulse Control Disorder, an Obsessive-Compulsive Disorder or in light of the overlap of characteristics with both Gaming and Gambling Disorder as an addictive behavior. The overlapping features are: loss of control over the respective excessive behavior, giving …

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The Basal Forebrain Cholinergic Nuclei and Their Relevance to Schizophrenia and Other Psychotic Disorders

In this review, the specific role of the basal forebrain cholinergic nuclei (BFCN) and their projections are discussed from a neuroimaging perspective and with a focus on psychotic disorders alongside future directions. These directions set the stage for the development of new treatment targets for psychotic disorders. For more information see: Eickhoff, S., Franzen, L., …

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[Treatment of obsessive-compulsive disorders: recommendations of the revised S3 guidelines on obsessive-compulsive disorders]

Our new publication “[Treatment of obsessive-compulsive disorders: recommendations of the revised S3 guidelines on obsessive-compulsive disorders]” (Voderholzer et al., 2022) out in Der Nervenarzt with contribution by Bartosz Zurowski! More information you can find here: Voderholzer, U., Favreau, M., Rubart, A., Staniloiu, A., Wahl-Kordon, A., Zurowski, B., & Kathmann, N. (2022). Therapie der Zwangsstörungen: Empfehlungen …

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Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes

In this new study, we identified two transdiagnostic, neuroanatomically informed clusters that are clinically and biologically distinct and challenge current diagnostic boundaries in recent-onset mental health disorders. These findings may help to transdiagnostically understand the etiology of patients with poor outcomes and improve the development of stratified treatments. For more information see: Lalousis, P. A., …

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Obesity and brain structure in schizophrenia

In the new publication “Obesity and brain structure in schizophrenia – ENIGMA study in 3021 individuals” (McWhinney et al., 2022) in Molecular Psychiatry, we confirmed widespread associations between BMI and brain structure in individuals with schizophrenia. People with both obesity and schizophrenia showed more pronounced brain alterations than people with only one of these conditions. …

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