Consultant psychiatrist principal investigator
- Jolanta Chwalko (study nurse)
- Andrea Eichler (study nurse)
- Birgit Kilb (study assistant)
- Janika Tuulia Konttinen (psychologist)
- Dr Ines Wilhelm-Groch (psychologist)
1984-1985 Study on Onchocercosis in LIberia and at the Bernhard Nocht Institute Hamburg (DE)
1985-1993 Neurologist at the St. Georg Hospital Hamburg (DE)
1993-1996 Psychiatrist at the University of Luebeck (DE)
Since 1997 Consultant Psychiatrist, Principal Investigator of clinical studies on alcoholism and on sleep disorders,
Since 2019 Head of the Track for Addiction Therapy and Sleep Medicine
1983 Medical Degree, University of Hamburg (DE)
1985 PhD University of Hamburg (DE)
1993 MA of Philosophy at the University of Hamburg (DE),
1996 Board Certification in Psychiatry and Psychotherapy (Luebeck, DE)
2006 Habilitation/venia legendi University of Luebeck (DE),
since 2011: Professor at the University of Luebeck (DE)
Translational research in alcoholism with a special focus on stress reagibility and risk of early relapse, and research on insomnia with a special focus on overnight memory consolidation
1: Suslow T, Junghanns K, Weitzsch C, Arolt V. Relations between
neuropsychological vulnerability markers and negative symptoms in schizophrenia.
Psychopathology. 1998;31(4):178-87. doi: 10.1159/000029038. PMID: 9697161.
2: Wetterling T, Tessmann G, Junghanns K. Aufklärung über Medikamente [Informing
psychiatric patients about medication – results of a query]. Psychiatr Prax.
2002 Jul;29(5):235-9. German. doi: 10.1055/s-2002-32710. PMID: 12101488.
3: Wetterling T, Junghanns K. Psychiatrischer Konsiliardienst bei älteren
Patienten. Anderungen der Anforderungen durch Inkrafttreten des Betreuungs- und
Gesundheitsstrukturgesetzes? [Psychiatric consultation services for the elderly.
Changes in utilization due to the new German legislation concerning guardianship
and restructuring of health care providers]. Nervenarzt. 2000 Jul;71(7):559-64.
German. doi: 10.1007/s001150050626. PMID: 10989810.
4: Wetterling T, Junghanns K, Dilling H. Qualitätssicherung in der
psychiatrischen Klinik. Wie können die Therapieergebnisse möglichst einfach
erfasst werden? [Quality assurance in the psychiatric clinic. How can therapy
outcome be assessed in a preferably easy manner?]. Psychiatr Prax. 1998
Nov;25(6):291-5. German. PMID: 9885842.
5: Wetterling T, Junghanns K, Müssigbrodt H, Freyberger HJ, Dilling H. Erfassung
der Therapie Ergebnisse im Rahmen der Qualitätssicherung in einer
psychiatrischen Klinik. Ein Erfahrungsbericht [Assessment of therapy outcome
within the scope of quality assurance in a psychiatric clinic. A report of
experiences]. Nervenarzt. 1997 Sep;68(9):742-51. German. doi:
10.1007/s001150050189. PMID: 9411277.
6: Junghanns K, Backhaus J, Tietz U, Lange W, Bernzen J, Wetterling T, Rink L,
Driessen M. Impaired serum cortisol stress response is a predictor of early
relapse. Alcohol Alcohol. 2003 Mar-Apr;38(2):189-93. doi: 10.1093/alcalc/agg052.
PMID: 12634269.
7: Junghanns K, Backhaus J, Veltrup C, Dageförde J, Brückmann H, Wetterling T.
Mildly disturbed hepatic and pancreatic function during early abstention from
alcohol is associated with brain atrophy and with disturbed psychometric
performance. Alcohol Alcohol. 2004 Mar-Apr;39(2):113-8. doi:
10.1093/alcalc/agh028. PMID: 14998827.
8: Driessen M, Veltrup C, Junghanns K, Przywara A, Dilling H. Kosten-Nutzen-
Analyse klinisch-evaluierter Behandlungsprogramme. Erweiterte Entzugstherapie
bei Alkoholabhängigkeit [Cost-efficacy analysis of clinically evaluated
therapeutic programs. An expanded withdrawal therapy in alcohol dependence].
Nervenarzt. 1999 May;70(5):463-70. German. doi: 10.1007/s001150050463. PMID:
10407843.
9: Suslow T, Arolt V, Junghanns K. Alexithymie und automatische Aktivierung
emotional-evaluativer Informationen [Alexithymia and automatic activation of
emotional-evaluative information]. Psychother Psychosom Med Psychol. 1998
May;48(5):168-75. German. PMID: 9632952.
10: Lencer R, Trillenberg P, Trillenberg-Krecker K, Junghanns K, Kordon A,
Broocks A, Hohagen F, Heide W, Arolt V. Smooth pursuit deficits in
schizophrenia, affective disorder and obsessive-compulsive disorder. Psychol
Med. 2004 Apr;34(3):451-60. doi: 10.1017/s0033291703001314. PMID: 15259830.
11: Driessen M, Lange W, Junghanns K, Wetterling T. Proposal of a comprehensive
clinical typology of alcohol withdrawal–a cluster analysis approach. Alcohol
Alcohol. 2005 Jul-Aug;40(4):308-13. doi: 10.1093/alcalc/agh167. Epub 2005 May
16. PMID: 15897220.
12: Junghanns K, Koch J, Sprenger A. Track D. FS: New developments in the
analysis and modification of central nervous rhythms. Biomed Tech (Berl). 2015
Sep;60 Suppl 1:s47-s102. doi: 10.1515/bmt-2015-5003. PMID: 26360485.
13: Wetterling T, Junghanns K. Gerontopsychiatrischer Konsiliardienst
[Gerontopsychiatric consultation service]. Psychiatr Prax. 2002 Sep;29(6):311-4.
German. doi: 10.1055/s-2002-34040. PMID: 12224041.
14: Backhaus J, Junghanns K, Hohagen F. Diagnostik und Therapie von
Schlafstörungen. Frühzeitig nachfragen–rechtzeitig behandeln [Diagnosis and
therapy of sleep disorders. Early assessment–prompt treatment]. MMW Fortschr
Med. 2002 May 6;Suppl 2:12-6. German. PMID: 12070844.
15: Wurst FM, Graf I, Ehrenthal HD, Klein S, Backhaus J, Blank S, Graf M,
Pridzun L, Wiesbeck GA, Junghanns K. Gender differences for ghrelin levels in
alcohol-dependent patients and differences between alcoholics and healthy
controls. Alcohol Clin Exp Res. 2007 Dec;31(12):2006-11. doi:
10.1111/j.1530-0277.2007.00527.x. Epub 2007 Oct 19. PMID: 17949465.
16: Driessen M, Meier S, Hill A, Wetterling T, Lange W, Junghanns K. The course
of anxiety, depression and drinking behaviours after completed detoxification in
alcoholics with and without comorbid anxiety and depressive disorders. Alcohol
Alcohol. 2001 May-Jun;36(3):249-55. doi: 10.1093/alcalc/36.3.249. PMID:
11373263.
17: Wetterling T, Backhaus J, Junghanns K. Sucht im Alter Ein unterschätztes
Problem in der klinischen Versorgung älterer Menschen? [Addiction in the elderly
– an underestimated diagnosis in clinical practice?]. Nervenarzt. 2002
Sep;73(9):861-6. German. doi: 10.1007/s00115-002-1359-3. PMID: 12215877.
18: Trillenberg P, Heide W, Junghanns K, Blankenburg M, Arolt V, Kömpf D. Target
anticipation and impairment of smooth pursuit eye movements in schizophrenia.
Exp Brain Res. 1998 Jun;120(3):316-24. doi: 10.1007/s002210050405. PMID:
9628418.
19: Backhaus J, Junghanns K, Born J, Hohaus K, Faasch F, Hohagen F. Impaired
declarative memory consolidation during sleep in patients with primary insomnia:
Influence of sleep architecture and nocturnal cortisol release. Biol Psychiatry.
2006 Dec 15;60(12):1324-30. doi: 10.1016/j.biopsych.2006.03.051. Epub 2006 Jul
28. PMID: 16876140.
20: Junghanns K, Graf I, Pflüger J, Wetterling G, Ziems C, Ehrenthal D, Zöllner
M, Dibbelt L, Backhaus J, Weinmann W, Wurst FM. Urinary ethyl glucuronide (EtG)
and ethyl sulphate (EtS) assessment: valuable tools to improve verification of
abstention in alcohol-dependent patients during in-patient treatment and at
follow-ups. Addiction. 2009 Jun;104(6):921-6. doi:
10.1111/j.1360-0443.2009.02566.x. PMID: 19466918.
21: Junghanns K, Backhaus J, Tietz U, Lange W, Rink L, Wetterling T, Driessen M.
The consumption of cigarettes, coffee and sweets in detoxified alcoholics and
its association with relapse and a family history of alcoholism. Eur Psychiatry.
2005 Aug;20(5-6):451-5. doi: 10.1016/j.eurpsy.2004.09.011. PMID: 16171658.
22: Backhaus J, Junghanns K, Mueller-Popkes K, Broocks A, Riemann D, Hajak G,
Hohagen F. Short-term training increases diagnostic and treatment rate for
insomnia in general practice. Eur Arch Psychiatry Clin Neurosci. 2002
Jun;252(3):99-104. doi: 10.1007/s00406-002-0361-x. PMID: 12192465.
23: Spengler D, Trillenberg P, Sprenger A, Nagel M, Kordon A, Junghanns K, Heide
W, Arolt V, Hohagen F, Lencer R. Evidence from increased anticipation of
predictive saccades for a dysfunction of fronto-striatal circuits in obsessive-
compulsive disorder. Psychiatry Res. 2006 Jun 30;143(1):77-88. doi:
10.1016/j.psychres.2005.08.020. Epub 2006 May 30. PMID: 16730377.
24: Backhaus J, Born J, Hoeckesfeld R, Fokuhl S, Hohagen F, Junghanns K. Midlife
decline in declarative memory consolidation is correlated with a decline in slow
wave sleep. Learn Mem. 2007 May 1;14(5):336-41. doi: 10.1101/lm.470507. PMID:
17522024; PMCID: PMC1876757.
25: Wetterling T, Weber B, Depfenhart M, Schneider B, Junghanns K. Development
of a rating scale to predict the severity of alcohol withdrawal syndrome.
Alcohol Alcohol. 2006 Nov-Dec;41(6):611-5. doi: 10.1093/alcalc/agl068. Epub 2006
Sep 16. PMID: 16980710.
26: Sun L, König IR, Jacobs A, Seitz HK, Junghanns K, Wagner T, Ludwig D,
Jacrobs A, Homann N. Mean corpuscular volume and ADH1C genotype in white
patients with alcohol-associated diseases. Alcohol Clin Exp Res. 2005
May;29(5):788-93. doi: 10.1097/01.alc.0000163500.81691.74. PMID: 15897724.
27: Junghanns K, Tietz U, Dibbelt L, Kuether M, Jurth R, Ehrenthal D, Blank S,
Backhaus J. Attenuated salivary cortisol secretion under cue exposure is
associated with early relapse. Alcohol Alcohol. 2005 Jan-Feb;40(1):80-5. doi:
10.1093/alcalc/agh107. Epub 2004 Nov 18. PMID: 15550447.
28: Junghanns K, Horbach R, Ehrenthal D, Blank S, Backhaus J. Cortisol awakening
response in abstinent alcohol-dependent patients as a marker of HPA-axis
dysfunction. Psychoneuroendocrinology. 2007 Sep-Nov;32(8-10):1133-7. doi:
10.1016/j.psyneuen.2007.06.012. Epub 2007 Aug 3. PMID: 17689018.
29: Homann N, Stickel F, König IR, Jacobs A, Junghanns K, Benesova M, Schuppan
D, Himsel S, Zuber-Jerger I, Hellerbrand C, Ludwig D, Caselmann WH, Seitz HK.
Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol-associated
cancer in heavy drinkers. Int J Cancer. 2006 Apr 15;118(8):1998-2002. doi:
10.1002/ijc.21583. PMID: 16287084.
30: Sommer M, Braumann M, Althoff T, Backhaus J, Kordon A, Junghanns K,
Ehrenthal D, Bartmann U, Hohagen F, Broocks A. Psychological and neuroendocrine
responses to social stress and to the administration of the alpha-2-receptor
antagonist, yohimbine, in highly trained endurance athletes in comparison to
untrained healthy controls. Pharmacopsychiatry. 2011 Jun;44(4):129-34. doi:
10.1055/s-0031-1277166. Epub 2011 Jun 27. PMID: 21710402.
31: Wetterling T, Veltrup C, Junghanns K, Krömer-Olbrisch T, Schneider U.
Acceptance of pharmacotherapy for relapse prevention by chronic alcoholics.
Pharmacopsychiatry. 2001 Jul;34(4):142-6. doi: 10.1055/s-2001-15874. PMID:
11518475.
32: Backhaus J, Hoeckesfeld R, Born J, Hohagen F, Junghanns K. Immediate as well
as delayed post learning sleep but not wakefulness enhances declarative memory
consolidation in children. Neurobiol Learn Mem. 2008 Jan;89(1):76-80. doi:
10.1016/j.nlm.2007.08.010. Epub 2007 Oct 29. PMID: 17911036.
33: Junghanns K, Horbach R, Ehrenthal D, Blank S, Backhaus J. Chronic and high
alcohol consumption has a negative impact on sleep and sleep-associated
consolidation of declarative memory. Alcohol Clin Exp Res. 2009 May;33(5):893-7.
doi: 10.1111/j.1530-0277.2009.00909.x. Epub 2009 Mar 11. PMID: 19320630.
34: Backhaus J, Junghanns K, Hohagen F. Sleep disturbances are correlated with
decreased morning awakening salivary cortisol. Psychoneuroendocrinology. 2004
Oct;29(9):1184-91. doi: 10.1016/j.psyneuen.2004.01.010. PMID: 15219642.
35: Wetterling T, Junghanns K. Psychopathology of alcoholics during withdrawal
and early abstinence. Eur Psychiatry. 2000 Dec;15(8):483-8. doi:
10.1016/s0924-9338(00)00519-8. PMID: 11175926.
36: Katofsky I, Backhaus J, Junghanns K, Rumpf HJ, Hüppe M, von Eitzen U,
Hohagen F. Effectiveness of a cognitive behavioral self-help program for
patients with primary insomnia in general practice – a pilot study. Sleep Med.
2012 May;13(5):463-8. doi: 10.1016/j.sleep.2011.12.008. Epub 2012 Feb 17. PMID:
22342027.
37: Suslow T, Junghanns K, Arolt V. Detection of facial expressions of emotions
in depression. Percept Mot Skills. 2001 Jun;92(3 Pt 1):857-68. doi:
10.2466/pms.2001.92.3.857. PMID: 11453215.
38: Wetterling T, Driessen M, Kanitz RD, Junghanns K. The severity of alcohol
withdrawal is not age dependent. Alcohol Alcohol. 2001 Jan-Feb;36(1):75-8. doi:
10.1093/alcalc/36.1.75. PMID: 11139420.
39: Berking M, Margraf M, Ebert D, Wupperman P, Hofmann SG, Junghanns K.
Deficits in emotion-regulation skills predict alcohol use during and after
cognitive-behavioral therapy for alcohol dependence. J Consult Clin Psychol.
2011 Jun;79(3):307-18. doi: 10.1037/a0023421. PMID: 21534653; PMCID: PMC3109184.
40: Wetterling T, Dibbelt L, Wetterling G, Göder R, Wurst F, Margraf M,
Junghanns K. Ethyl glucuronide (EtG): better than breathalyser or self-reports
to detect covert short-term relapses into drinking. Alcohol Alcohol. 2014 Jan-
Feb;49(1):51-4. doi: 10.1093/alcalc/agt155. Epub 2013 Oct 16. PMID: 24133131.
41: Brüggemann N, Wandinger KP, Gaig C, Sprenger A, Junghanns K, Helmchen C,
Münchau A. Dystonia, lower limb stiffness, and upward gaze palsy in a patient
with IgLON5 antibodies. Mov Disord. 2016 May;31(5):762-4. doi:
10.1002/mds.26608. Epub 2016 Mar 31. PMID: 27030137.
42: Göder R, Baier PC, Beith B, Baecker C, Seeck-Hirschner M, Junghanns K,
Marshall L. Effects of transcranial direct current stimulation during sleep on
memory performance in patients with schizophrenia. Schizophr Res. 2013
Mar;144(1-3):153-4. doi: 10.1016/j.schres.2012.12.014. Epub 2013 Jan 18. PMID:
23336963.
43: Broocks A, Junghanns K, Thiel A, Gleiter CH, Bandelow B. Neue Antidepressiva
im Vergleich zu klassischen Trizyklika. Wirkmechanismen und klinische
Beurteilung [New antidepressive drugs in comparison with classical tricyclics.
Mechanism of action and clinical evaluation]. Fortschr Neurol Psychiatr. 2000
Jan;68(1):17-24. German. doi: 10.1055/s-2000-11639. PMID: 10705571.
44: Junghanns K, Veltrup C, Wetterling T. Craving shift in chronic alcoholics.
Eur Addict Res. 2000 Jun;6(2):64-70. doi: 10.1159/000019012. PMID: 10899731.
45: Backhaus J, Junghanns K. Daytime naps improve procedural motor memory. Sleep
Med. 2006 Sep;7(6):508-12. doi: 10.1016/j.sleep.2006.04.002. Epub 2006 Aug 23.
PMID: 16931152.
46: Göder R, Graf A, Ballhausen F, Weinhold S, Baier PC, Junghanns K, Prehn-
Kristensen A. Impairment of sleep-related memory consolidation in schizophrenia:
relevance of sleep spindles? Sleep Med. 2015 May;16(5):564-9. doi:
10.1016/j.sleep.2014.12.022. Epub 2015 Mar 14. PMID: 25912599.
47: Wetterling T, Junghanns K. Affective disorders in older inpatients. Int J
Geriatr Psychiatry. 2004 May;19(5):487-92. doi: 10.1002/gps.943. PMID: 15156551.
48: Wurst FM, Rasmussen DD, Hillemacher T, Kraus T, Ramskogler K, Lesch O,
Bayerlein K, Schanze A, Wilhelm J, Junghanns K, Schulte T, Dammann G, Pridzun L,
Wiesbeck G, Kornhuber J, Bleich S. Alcoholism, craving, and hormones: the role
of leptin, ghrelin, prolactin, and the pro-opiomelanocortin system in modulating
ethanol intake. Alcohol Clin Exp Res. 2007 Dec;31(12):1963-7. doi:
10.1111/j.1530-0277.2007.00531.x. PMID: 18034691.
49: Adinoff B, Junghanns K, Kiefer F, Krishnan-Sarin S. Suppression of the HPA
axis stress-response: implications for relapse. Alcohol Clin Exp Res. 2005
Jul;29(7):1351-5. doi: 10.1097/01.alc.0000176356.97620.84. Erratum in: Alcohol
Clin Exp Res. 2006 Mar;30(3):585. PMID: 16088999; PMCID: PMC2584966.
Project Grants of the DAAD: Study on Onchocercosis in a hypoendemic area in Liberia; as PI: Research Group Memory and Sleep (DFG-Grant 2002-5: DM 158.000), Neuroplasticityx and Sleep (2005-9: DFG Grant € 300.000), Study on the influence of memory training in alcohlics (Grant from vffr-sh: €90.000), Grant on Nightly memory consolidation in primary and secondary insomnia (DFG Grant €245.000), Studies on emotionally charged or behaviorally relevant memory during sleep of patient with psychiatric disorders (DFG Grant within TR-SFB 654, €420.000); 2016-20: PI in industrial multicentric phase 3 studies on pharmaceuticals in insomnie: € 740.000, 2018-20 PI in a study on the effect of kale on sleep: grant of the WTSH (€ 100.000)